RosettaCommons - Karanicolas

Druggable protein interaction sites are more predisposed to surface pocket formation than the rest of the protein surface.

Sun, 22 Mar 2015 01:34:32 +0000

Authors:

Johnson DK, Karanicolas J

Link to article:

http://www.ncbi.nlm.nih.gov/pubmed/?term=23505360

Volume:

Year:

2013

Source:

PLoS Comput Biol

Pages:

e1002951

Lab:

Karanicolas

Publication Subject:

Other Rosetta Papers

Publication Type:

Method

PubMed ID:

23505360

Status:

confirmed

Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen.

Sun, 22 Mar 2015 01:33:54 +0000

Authors:

Thomas JC, O'Hara JM, Hu L, Gao FP, Joshi SB, Volkin DB, Brey RN, Fang J, Karanicolas J, Mantis NJ, Middaugh CR

Link to article:

http://www.ncbi.nlm.nih.gov/pubmed/?term=23563512

Volume:

Year:

2013

Source:

Hum Vaccin Immunother

Pages:

744-52

Lab:

Karanicolas

Publication Subject:

Protein Design

Publication Type:

Application

PubMed ID:

23563512

Status:

confirmed

Fast docking on graphics processing units via Ray-Casting.

Sun, 22 Mar 2015 01:33:18 +0000

Authors:

Khar KR, Goldschmidt L, Karanicolas J

Link to article:

http://www.ncbi.nlm.nih.gov/pubmed/?term=23976948

Volume:

Year:

2013

Source:

PLoS One

Pages:

e70661

Lab:

Karanicolas

Publication Subject:

Ligand Docking

Publication Type:

Method

PubMed ID:

23976948

Status:

confirmed

The designability of protein switches by chemical rescue of structure: mechanisms of inactivation and reactivation.

Sun, 22 Mar 2015 01:31:55 +0000

Authors:

Xia Y, DiPrimio N, Keppel TR, Vo B, Fraser K, Battaile KP, Egan C, Bystroff C, Lovell S, Weis DD, Anderson JC, Karanicolas J

Link to article:

http://www.ncbi.nlm.nih.gov/pubmed/?term=24313858

Volume:

135

Year:

2013

Source:

J Am Chem Soc

Pages:

18840-9

Lab:

Karanicolas

Publication Subject:

Protein Design

Publication Type:

Application

PubMed ID:

24313858

Status:

confirmed

Selectivity by small-molecule inhibitors of protein interactions can be driven by protein surface fluctuations.

Sun, 22 Mar 2015 01:31:29 +0000

Authors:

Johnson DK, Karanicolas J

Link to article:

http://www.ncbi.nlm.nih.gov/pubmed/?term=25706586

Volume:

Year:

2015

Source:

PLoS Comput Biol

Pages:

e1004081

Lab:

Karanicolas

Publication Subject:

Other Rosetta Papers

Publication Type:

Method

PubMed ID:

25706586

Status:

confirmed