Control of protein signaling using a computationally designed GTPase/GEF orthogonal pair.
Submitted by Anonymous on Sun, 2015-03-15 12:11
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Interface & Interface Design
Quantification of the transferability of a designed protein specificity switch reveals extensive epistasis in molecular recognition.
Submitted by Anonymous on Sun, 2015-03-15 12:09
Reliable cell cycle commitment in budding yeast is ensured by signal integration.
Submitted by Anonymous on Sun, 2015-03-15 08:06
A simple physical model for binding energy hot spots in protein-protein complexes.
Submitted by Anonymous on Sun, 2015-03-15 06:45
Design, activity, and structure of a highly specific artificial endonuclease.
Submitted by Anonymous on Sun, 2015-03-15 06:45
Symmetry recognizing asymmetry: analysis of the interactions between the C-type lectin-like immunoreceptor NKG2D and MHC class I-like ligands.
Submitted by Anonymous on Sun, 2015-03-15 06:45
Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130.
Submitted by Anonymous on Sun, 2015-03-15 06:45
Computational alanine scanning of protein-protein interfaces.
Submitted by Anonymous on Sun, 2015-03-15 06:45
Computational redesign of protein-protein interaction specificity.
Submitted by Anonymous on Sun, 2015-03-15 06:45
Rational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesion.
Submitted by Anonymous on Sun, 2015-03-15 06:45