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Computational design of the sequence and structure of a protein-binding Peptide

Submitted by admin on Tue, 2011-04-05 00:26
Authors: 
Sammond DW, Bosch DE, Butterfoss GL, Purbeck C, Machius M, Siderovski DP, Kuhlman B
Volume: 
133
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/21388199
Year: 
2011
Reference: 
J Am Chem Soc
Pages: 
4190-2
Lab: 
Kuhlman
Publication Type: 
Application
Publication Subject: 
Interface & Interface Design

Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening

Submitted by admin on Tue, 2011-04-05 00:22
Authors: 
Mueller R, Rodriguez AL, Dawson ES, Butkiewicz M, Nguyen TT, Oleszkiewicz S, Bleckmann A, Weaver CD, Lindsley CW, Conn PJ, Meiler J
Volume: 
1
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/20414370
Year: 
2010
Reference: 
ACS Chem Neurosci
Pages: 
288-305
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Applications

Unique gating properties of C. elegans ClC anion channel splice variants are determined by altered CBS domain conformation and the R-helix linker

Submitted by admin on Tue, 2011-04-05 00:18
Authors: 
Dave S, Sheehan JH, Meiler J, Strange K
Volume: 
4
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/20581474
Year: 
2010
Reference: 
Channels
Pages: 
289-301
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Applications

Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential

Submitted by admin on Tue, 2011-04-05 00:14
Authors: 
Gregory KJ, Dong EN, Meiler J, Conn PJ
Volume: 
60
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/20637216
Year: 
2011
Reference: 
Neuropharmacology
Pages: 
66-81
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Applications

3D-QSAR CoMFA study of benzoxazepine derivatives as mGluR5 positive allosteric modulators

Submitted by admin on Tue, 2011-04-05 00:13
Authors: 
Lowe EW Jr, Ferrebee A, Rodriguez AL, Conn PJ, Meiler J
Volume: 
20
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/20732812
Year: 
2010
Reference: 
ioorg Med Chem Lett
Pages: 
5922-4
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Protein Design

Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel

Submitted by admin on Tue, 2011-04-05 00:11
Authors: 
Bhave G, Chauder BA, Liu W, Dawson ES, Kadakia R, Nguyen TT, Lewis LM, Meiler J, Weaver CD, Satlin LM, Lindsley CW, Denton JS
Volume: 
79
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/20926757
Year: 
2011
Reference: 
Mol Pharmacol
Pages: 
42-50
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Protein Design

RosettaEPR: an integrated tool for protein structure determination from sparse EPR data

Submitted by admin on Tue, 2011-04-05 00:10
Authors: 
Hirst SJ, Alexander N, McHaourab HS, Meiler J
Volume: 
173
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/21029778
Year: 
2011
Reference: 
J Struct Biol
Pages: 
506-14
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Modeling With Experimental Constraints

Computational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linking

Submitted by admin on Tue, 2011-04-05 00:08
Authors: 
Kalkhof S, Haehn S, Paulsson M, Smyth N, Meiler J, Sinz A
Volume: 
78
Link to Article: 
http://www.ncbi.nlm.nih.gov/pubmed/20939100
Year: 
2010
Reference: 
Proteins
Pages: 
3409-27
Lab: 
Meiler
Publication Type: 
Application
Publication Subject: 
Modeling With Experimental Constraints

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